evaluation of elisa and brucellacapt tests for diagnosis of human brucellosis.

Evaluation of ELISA and Brucellacapt tests for diagnosis of human Brucellosis

BACKGROUND AND OBJECTIVES Brucellosis is one of the most common zoonotic diseases in Iran and human brucellosis is endemic in all parts of the country. Because of the difficulty in the diagnosis of brucellosis, particularly in endemic areas, the use of new and feasible diagnostic tests seem to be of great importance for resolving the diagnostic obstacles. We evaluated the usefulness of a new se...

BRUCELLACAPT vs. CLASSICAL TESTS IN THE SEROLOGICAL DIAGNOSIS AND MANAGEMENT OF HUMAN BRUCELLOSIS

BrucellaCapt versus classical tests in the serological diagnosis and management of human brucellosis.

The BrucellaCapt test is an immunocapture agglutination test suggested as a possible substitute for the Coombs test in the diagnosis of human brucellosis. Here it is compared with classical tests using 321 samples from 48 patients with brucellosis (6.9 +/- 1.7 samples per patient), including 20 patients with focal disease and 8 patients with a total of 9 relapse episodes (mean follow-up, 18 mon...

A Comparative Evaluation of ELISA, PCR, and Serum Agglutination Tests For Diagnosis of Brucella Using Human Serum

Background & Objective: Since the symptoms of Brucellosis are often atypical and nonspecific, using clinical signs alone to diagnose brucellosis is not advised; therefore, the diagnosis relies predominantly on laboratory testing. Currently, molecular, serological, and microbiological methods are used for diagnosis of this disease. In this study we examined ELI...

ELISA Cut-off Point for the Diagnosis of Human Brucellosis; a Comparison with Serum Agglutination Test

Background: Brucellosis is a world-wide disease, which has a diverse clinical manifestation, and its diagnosis has to be proven by laboratory data. Serum agglutination test (SAT) is the most-widely used test for diagnosing brucellosis. The enzyme linked immunosorbent assay (ELISA) can also determine specific antibody classes against brucella. It is a sensitive, simple and rapid test, which coul...

The Iportance of Agglutination tests versus ELISA in the diagnosis of brucellosis

Background: Brucellosis is one of the endemic and a Zoonotic disease of the Iran. Science the rapid diagnosis and quick treatment are very important, selection of a sensitive and specific test solving this problem is of a great importance. The main aim of this study is comparison of routine serologic test with standard Elisa test. Materials and methods: In this survey, 176 suspected patient...